Preheat oven to 350°. Line a 13x9x2 inch baking pan with foil; coat foil with cooking spray. Set aside.
In a large microwave-safe bowl melt butter. Whisk in sugar, instant coffee, and vanilla. Add eggs and whisk for 2 minutes. Set aside.
In a medium mixing bowl, whisk together ground chocolate, flour, baking powder, and salt until blended. Add all at once to butter mixture and stir just until blended. Stir in chocolate chips just until blended. Set aside.
In mixer, beat cream cheese with sugar until smooth. Add eggs and whiskey and beat until smooth.
Layer half of the brownie batter in prepared pan. Cover with cream cheese mixture, spreading evenly and all the way to edges. Top with remaining brownie mixture, spreading to cover cream cheese layer.
Bake in preheated oven for 50 minutes; or until a toothpick comes out clean.
Let brownies cool completely.
Melt white chocolate chips with Irish whiskey. Drizzle over brownies. Let cool, then cut and serve.
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